RNA Details
Disease Name
silicosis
Tissue
lung
RNA Symbol
Ambra1
RNA ID
RNA Type
mRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
Immunohistochemistry; qRT-PCR; Western Blot etc.
Target
NA
Pathway
NA
PubMed ID
Title
MicroRNA-205-5p targets E2F1 to promote autophagy and inhibit pulmonary fibrosis in silicosis through impairing SKP2-mediated Beclin1 ubiquitination
Year
2021
Function
"Taken together, these results revealed the upregulated expression of Beclin1 in silicosis, which may be attributed to the lung self-protective mechanism."